College football picks, schedule: predictions against the spread, odds for top 25 games today in week 6

Another fraught college football Saturday is upon us with 19 ranked teams in action plus three key matches between top-25 opponents. Disruptions and shifts in expectation were the name of the game during the first five weeks of the 2021 season, and there’s every chance it will continue into Week 6 with teams like No. 7 Ohio State, No. 10 BYU, No. 9 Michigan and No. 14 Notre Dame, including in matches against unranked but talented competition.

However, there are four standout games of the day, starting with No. 6 Oklahoma and No. 21 Texas in the latest edition of the Red River Showdown. The Sooners have won three in a row and five of the last six in the series, but the Longhorns believe they found something with Casey Thompson’s one-two punch as quarterback and Bijan Robinson as running back. Georgia’s seemingly impenetrable defense will endure the toughest test of the season as it takes on No. 18 Auburn and QB Bo Nix, while No. 3 Iowa hopes its defense continues its incredible turnover binge against a No. 4 Penn State team is feeling thanks to QB Sean Clifford. In the nightcap, No. 1 Alabama and Texas A&M go head to head with coach Nick Saban looking to improve to 25-0 against his former assistants, while Jimbo Fisher continues to look for answers for an Aggies squad that has impressed this season. .

While winning is all that matters for the standings, we think it’s important that these teams cover their spreads. Be sure to stick with CBS Sports all day for college football coverage from Saturday’s opening kick-off to the final whistle. Let’s take a look at our roster of experts for the fifth full Saturday of the season.

Opportunities through Caesars Sportsbook | All times Eastern

No. 6 Oklahoma vs. No. 21 Texas

Last Chances:

Oklahoma Sooners -3.5

Afternoon | ABC, fuboTV (Try for free) — It’s hard to know which version of each team we’ll get in the Red River Showdown. Is Texas the team that lost 70 points to Texas Tech or the team that struggled against a similar TCU squad? Does Oklahoma play its cards close to the vest, or is it systematically offending? My money is on Oklahoma coach Lincoln Riley unleashing the running backs against his team’s first-ranked opponent of the season and the defense taking advantage of a Texas offense that is still gaining a foothold. Prediction: Oklahoma (-3) – Shehan Jeyarajah

no. 2 Georgia at No. 18 Auburn

Last Chances:

Georgia Bulldogs -15

3.30 pm | CBS, CBSSports.com, CBS Sports AppThe best way for Georgia to stop quarterback Bo Nix from using his magic is to keep him on the sidelines, which is exactly what will happen. Whether it’s Stetson Bennett IV or JT Daniels starting below center, offensive coordinator Todd Monken will do everything he can to shorten the game knowing that one of his quarterbacks is smart enough to be in charge of the football. That said, Nix and his talented running back corps will do enough to make it a four-quarter game and keep it within two touchdowns. Forecast: Auburn (+14.5) –Barrett Sallee

No. 4 Penn State at No. 3 Iowa

Last Chances:

Iowa Hawkeyes -1.5

4 p.m. | Fox, fuboTV (Try for free) — My official pick here is Penn State and the points, but I’d be lying if I told you I had confidence in it. This game is a coin flip in my opinion. On the one hand, I don’t know if Iowa’s attack can get a long score if needed late. On the other hand, I’m not sure I can trust QB Sean Clifford down the road in a place like this. At the start of the year, Clifford struggled on the road against Wisconsin, and this defense in Iowa is just as strong. In this game it comes down to which team makes the fewest mistakes and both are able to force them. So in the end I just take the points in what should be an exciting game. Forecast: Penn State (+2.5) – Tom Fornell

no. 9 Michigan in Nebraska

Last Chances:

Michigan Wolverines -2.5

7:30 pm | ABC, fuboTV (Try for free) — I want to take advantage of perception here. Michigan is 5-0 and in the top 10, while Nebraska is 3-3, losing to Illinois. You are naive if you think that these factors have no influence on the point spread. Now, as I pluck the Cornhuskers to fix the outright upset, I’m not nearly as confident about that as the Huskers covering the spread. I find it hard to trust Michigan offense as road favorites against a team that can score points. Nebraska can score points. Forecast: Nebraska (+3) – Tom Fornell

No. 1 Alabama at Texas A&M

Last Chances:

Alabama Crimson Tide -18

8 p.m. | CBS, CBSSports.com, CBS Sports AppThis will be the best defense Alabama has faced since playing Florida, but the Aggies’ inability to move the football on offense will give the Crimson Tide offensive a lot more cracks. Expect the Aggies defense to bend without breaking a bit before the floodgates open in the third quarter. Prediction: Alabama (-17.5) — David Cobb

Which college football picks can you make with confidence in Week 6, and which national title contender will go down hard? Visit SportsLine to see which teams will win and cover the spread – all based on a proven computer model that has brought in nearly $3,400 in profits over the past five seasons – and find out.

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